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What are the four types of PCOS?

Laura Harcourt

Written byLaura Harcourt

Dr Shazia Malik

Reviewed byDr Shazia Malik

girl wearing cotton shirt and nose ring having relaxed facial expression, looking at camera

Summary

1Understanding the different types of PCOS

There are three main features of PCOS. These include: irregular periods, excess levels of male hormones in your body, which cause physical symptoms...

2Could it be something else?

PCOS can be difficult to diagnose because some of its most prominent symptoms can also have a variety of other causes. For example, irregular and...

3The final say

Knowing which PCOS type you have is like having a secret decoder. Once you have this information available, you’ll not only be able to better...

Polycystic ovary syndrome, often referred to as PCOS, is one of the most common women’s health issues, affecting approximately one in ten women around the world.1,2 However, it’s highly misunderstood and often misdiagnosed.

A hormone problem that affects how your ovaries work, PCOS gets its name from the numerous small, fluid-filled sacs that form in the ovaries in some people with PCOS.2 

But, the key word here is ‘some’, as not everyone with the condition will develop these.2 In fact, you could be affected and not even know – more than half of people with PCOS don’t experience any symptoms at all.2

In this guide, we take a closer look at the different types of PCOS and the key symptoms each one can cause.

Understanding the different types of PCOS

Before we get into the different types of PCOS, it’s important to start by looking at the condition as a whole. 

There are three main features of PCOS.2 These include:
  • irregular periods
  • excess levels of male hormones in your body, which can cause physical symptoms such as acne or increased hair growth 
  • enlarged ovaries (shown in an ultrasound) that contain more egg sacs (follicles) than normal 
While many people have heard of PCOS, far fewer are aware that there are different types of the condition. Each of these different types is classified based on their underlying cause.

That’s why if you suspect you may have PCOS, or you’re diagnosed with PCOS, it’s so important to find out which classification you have. 

Knowing this information means you can improve your understanding of your condition, helping you learn how to manage it, and any symptoms you have, effectively.

Type one: insulin-resistant PCOS

Many people who have PCOS are insulin resistant, which means that your body can make insulin, but it can’t use it effectively.3,4 Insulin resistance has been found to affect 50–70% of people with PCOS.5

Insulin is a hormone that’s made in your pancreas which manages the amount of sugar (glucose) in your blood. It also moves glucose from your blood into your cells where it’s used to create some of the energy your body uses every day.6

When you’re insulin resistant, this means that your body doesn’t respond to insulin as it should, or isn’t as sensitive to how insulin works, which leads to higher glucose levels.6

Too much glucose causes an imbalance in your normal hormone levels, which can not only lead to many of the symptoms associated with PCOS, such as weight gain, but also make them worse.7
meno misdiagnosis

Symptoms of insulin resistance in PCOS

There are certain signs of insulin resistance that are important to be aware of. These include:3,7
  • sleep apnea6,8 
  • depression/anxiety 
  • dark pigmentation and thickening of the skin in areas such as the neck, back, and armpits8

Getting diagnosed with insulin-resistant PCOS

Being diagnosed with insulin resistance PCOS can usually be done with blood tests to check your insulin and blood glucose levels.7,9 

These include the homeostatic model assessment (HOMA) and the oral glucose tolerance test (OGTT). These test for both insulin resistance and glucose intolerance.

While this is typically normal to low in women with PCOS, it could help indicate whether the amount of insulin in your blood is higher than the healthy threshold.10,11

Managing insulin-resistant PCOS

Once diagnosed, one of the most effective ways to manage insulin-resistant PCOS is to make positive changes to your lifestyle. Losing weight can be particularly effective, with a weight loss of just 5% leading to a significant improvement in PCOS symptoms.12 A healthy, balanced diet and regular exercise is the most effective formula for achieving sustainable weight loss.13,14

Following a low glycaemic index (GI) food plan can be particularly helpful – not just in terms of losing weight, but also in keeping it off. Low GI foods provide energy in a slower, steadier way compared to high GI foods which can make your blood sugar levels spike.13,14 

What’s more, a low GI food plan may also help reduce levels of insulin resistance, and the short and long-term issues commonly associated with hormonal imbalances.13,14

However, as there’s conflicting data regarding the impact of low GI foods on hormonal balance, and because PCOS carries significant metabolic risks, more research is needed.13-15

Metformin may also be recommended to help. Only available on prescription, this medication has been proven to be effective in both controlling blood sugars and reducing the negative effects of PCOS in carefully selected patients.16,17

Type two: inflammatory PCOS

Inflammation is part of the way that your body defends itself against bacteria, illnesses, and injury, and is used to start the healing process.

However, if you have inflammation in your body caused by illness or injury that doesn’t show symptoms right away, you may have what’s known as chronic inflammation.18 This type of inflammation can gradually sit in your body over a prolonged period of time, which can then start to damage the cells in your body.19 

Long-term, low-grade inflammation is a key contributor to PCOS,20 and some studies have found that people with PCOS have permanently raised levels of inflammation.21-24
meno nurse wh

Getting diagnosed with inflammatory PCOS

The best way to get a diagnosis of inflammatory PCOS is with a blood test. This can assess both the function of your ovaries and look at your inflammation markers (indicators in your blood) to see if they’re raised.21,22

Managing inflammatory PCOS

To manage inflammatory PCOS effectively, you could start by taking steps to lower the amount of inflammation in your body by making some changes to your diet. 

A Mediterranean diet, which is rich in antioxidants, omega-3 fatty acids, and fibre, has been shown to be effective at combating PCOS-related inflammation.25 Prioritise foods like salmon, sardines, spinach, kale, olive oil, whole grains, and nuts. 

Some other steps you can take to reduce inflammation include: 
  • take certain vitamin supplements, including vitamins A, C, D, and zinc26 
  • get regular exercise26
  • reach and maintain a healthy weight26 
  • find ways to manage your stress levels, such as through yoga or meditation26 
  • improve your gut health by actively promoting healthy bacteria in your gut through dietary changes and adding probiotics to your diet26 
There’s thought to be a connection between vitamin D deficiency and PCOS symptoms.27 One study reported that after 24 weeks, 50% of people with PCOS who took 24,000 IU vitamin D had improved menstrual disturbances.28 So, to help manage your insulin resistance, your doctor may suggest having your levels measured and taking vitamin D supplements if needed.

Type three: adrenal PCOS

Hyperandrogenism is a condition that occurs when you’ve got an excessive amount of sex hormones called androgens in your body.29

While both men and women have androgens in their bodies, men typically have a lot more which are instrumental in the development of “male” characteristics like body hair and a deeper voice.30 

The most well-known androgen is testosterone. In women, androgens are made in the ovaries and in the adrenal glands, which are small glands located on top of each of the kidneys. For this reason, this type of PCOS is sometimes known as adrenal PCOS.30 

Hyperandrogenism and PCOS are very closely connected, with one often influencing the other. It’s estimated that around 80% of women with hyperandrogenism also have PCOS.29,31 

One study reported that out of 154 participants with PCOS, 3.9% were found to be carriers of congenital adrenal hyperplasia (CAH). CAH carriers are thought to also have an increased risk of developing hyperandrogenism.31
women in striped jumper

Symptoms of adrenal PCOS

Many of the standard symptoms associated with PCOS also occur in hyperandrogenism.29 These include: 
  • oily skin 
  • acne
  • thick hair growth, particularly on the face, underarm area, pubic area, and limbs 
  • deep voice 
  • male pattern balding 
  • irregular periods
  • increased muscle mass

Getting diagnosed with adrenal PCOS

The most effective way of confirming adrenal PCOS is by taking blood tests to check your different hormone levels.32 

This information, combined with the symptoms you are experiencing, can help your doctor make a potential diagnosis.

Managing adrenal PCOS

The type of treatment you’re recommended will depend on whether PCOS alone is the cause of your condition.

Some of the most common medical treatments that may be given to help manage hyperandrogenism include oral contraceptives, and in some cases, medications such as diuretics or stronger anti-androgen medications, under the guidance of a specialist.33,34

Studies have also shown that weight loss can also be very beneficial in managing hyperandrogenism and PCOS.33,34
Young smiling woman wearing glasses holding smartphone using cellphone modern technology

Type four: post-pill PCOS

There’s a common misconception that hormonal contraceptives like the pill can cause PCOS to develop – often referred to as ‘post-pill PCOS’. However, there are no studies to prove that this is the case.
Instead, what you’re likely to experience when coming off the pill is a hormone fluctuation that causes symptoms that mimic those of PCOS, including irregular or missed periods.35 This is because it can take time for monthly menstruation to return after being on hormonal contraception.36 

You might also find that you start to experience PMS symptoms again, such as mood swings, acne, and bloating, which many people also attribute to PCOS. However, most of the effects of post-pill PCOS should subside as your hormones start to re-regulate.

It's important to be aware that, despite an irregular menstrual cycle, you can also get pregnant as soon as you stop taking the pill.

Could it be something else?

PCOS can be difficult to diagnose because some of its most prominent symptoms can also have a variety of other causes. For example, irregular and missed periods can be caused by gaining or losing a lot of weight, stress and anxiety, excessive exercising, and pregnancy – as well as PCOS.35 

Some other conditions that can often be mistaken for PCOS include thyroid disorders like hypothyroidism37 and Cushing’s Syndrome,38 as well as pituitary adenomas (benign tumours on the pituitary gland).39

If you have concerns about your diagnosis and have any reason to believe it’s incorrect, you should always feel free to seek a second opinion from your healthcare provider.

The final say

Like most health conditions, there’s no one-size-fits-all approach to treating PCOS. 

However, knowing which PCOS type you have is like having a secret decoder. Once you have this information available, you’ll not only be able to better manage your condition, but you’ll also be able to identify the right treatments to ease your symptoms

Sources

  1. Deswal, R., et al. The Prevalence of Polycystic Ovary Syndrome: A Brief Systematic Review. Journal of Human Reproductive Sciences, 2020;13(4):261–71. https://doi.org/10.4103/jhrs.JHRS_95_18.
  2. NHS. Polycystic Ovary Syndrome [Internet]. [cited 2024 Feb 21]. Available from: https://www.nhs.uk/conditions/polycystic-ovary-syndrome-pcos/.
  3. Purwar, A., et al. Insulin Resistance in Polycystic Ovarian Syndrome. Cureus, 2024;14(10):e30351. https://doi.org/10.7759/cureus.30351.
  4. Goodarzi, M. Looking for Polycystic Ovary Syndrome Genes: Rational and Best Strategy. Seminars in Reproductive Medicine, 2008;26(1):5–13. https://doi.org/10.1055/s-2007-992919.
  5. Rahman, M., et al. Role of Insulin in Health and Disease: An Update. International Journal of Molecular Sciences. 2021;22(12):6403 https://doi.org/10.3390/ijms22126403.
  6. Barber, T., et al. Obesity and Polycystic Ovary Syndrome: Implications for Pathogenesis and Novel Management Strategies. Clinical Medicine Insights. Reproductive Health, 2019;13:1179558119874042. https://doi.org/10.1177/1179558119874042.
  7. Legro RS, Castracane VD, Kauffman RP. Detecting Insulin Resistance in Polycystic Ovary Syndrome: Purposes and Pitfalls. Obstetrical & Gynecological Survey. 2004 Feb;59(2):141–54. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308732/
  8. National Institute of Diabetes and Digestive and Kidney Diseases. Insulin resistance & prediabetes. National Institute of Diabetes and Digestive and Kidney Diseases. 2018. Available from: https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/prediabetes-insulin-resistance
  9. Zhao H, Zhang J, Cheng X, Nie X, He B. Insulin resistance in polycystic ovary syndrome across various tissues: an updated review of pathogenesis, evaluation, and treatment. Journal of Ovarian Research. 2023 Jan 11;16(1). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832677/pdf/13048_2022_Article_1091.pdf 
  10. Conway, G., et al. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur J Endocrinol. 2014;171(4):P1–29. doi: 10.1530/EJE-14-0253.
  11. Kajaia N, Binder H, Dittrich R, et al. Low sex hormone-binding globulin as a predictive marker for insulin resistance in women with hyperandrogenic syndrome. European Journal of Endocrinology. 2007 Oct;157(4):499–507. Available from: https://pubmed.ncbi.nlm.nih.gov/17893265/
  12. Marsh K, Brand-Miller J. The optimal diet for women with polycystic ovary syndrome? The British journal of nutrition. 2005;94(2):154–65. Available from: https://www.ncbi.nlm.nih.gov/pubmed/16115348
  13. Cassar S, Misso ML, Hopkins WG, Shaw CS, Teede HJ, Stepto NK. Insulin resistance in polycystic ovary syndrome: a systematic review and meta-analysis of euglycaemic–hyperinsulinaemic clamp studies. Human Reproduction. 2016 Oct 7;31(11):2619–31. Available from: https://academic.oup.com/humrep/article/31/11/2619/2274340?login=false
  14. Marsh KA, Steinbeck KS, Atkinson FS, Petocz P, Brand-Miller JC. Effect of a low glycemic index compared with a conventional healthy diet on polycystic ovary syndrome. The American Journal of Clinical Nutrition. 2010 Jul 1;92(1):83–92. Available from: https://academic.oup.com/ajcn/article/92/1/83/4597432
  15. Chiavaroli L, Kendall CWC, Braunstein CR, et al. Effect of pasta in the context of low-glycaemic index dietary patterns on body weight and markers of adiposity: a systematic review and meta-analysis of randomised controlled trials in adults. BMJ open. 2018 Apr 2;8(3):e019438. Available from: https://pubmed.ncbi.nlm.nih.gov/29615407/
  16. Marshall, J., et al. All Women With PCOS Should Be Treated For Insulin Resistance. Fertility and Sterility, 2012;97(1):18–22. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277302/ https://doi.org/10.1016/j.fertnstert.2011.11.036.
  17. NHS. Treatment - Polycystic ovary syndrome. [Internet]. 2022. Available from: https://www.nhs.uk/conditions/polycystic-ovary-syndrome-pcos/treatment/
  18. Pahwa, R. Chronic Inflammation. StatPearls, StatPearls Publishing, 2024. PubMed, http://www.ncbi.nlm.nih.gov/books/NBK493173/.
  19. Chen, L., et al. Inflammatory Responses and Inflammation-Associated Diseases in Organs. Oncotarget, 2017;9(6):7204–18. https://doi.org/10.18632/oncotarget.23208.
  20. González, F. Inflammation in Polycystic Ovary Syndrome: Underpinning of Insulin Resistance and Ovarian Dysfunction. Steroids, 2012;77(4):300–05. https://doi.org/10.1016/j.steroids.2011.12.003.
  21. Regidor, P., et al. Chronic Inflammation in PCOS: The Potential Benefits of Specialized Pro-Resolving Lipid Mediators (SPMs) in the Improvement of the Resolutive Response. International Journal of Molecular Sciences, 2021;22(1):384. https://doi.org/10.3390/ijms22010384.
  22. Rudnicka E, Kunicki M, Suchta K, Machura P, Grymowicz M, Smolarczyk R. Inflammatory Markers in Women with Polycystic Ovary Syndrome. BioMed Research International. 2020 Mar 6;2020:1–10. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079227/
  23. Patel S. Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy. The Journal of Steroid Biochemistry and Molecular Biology. 2018 Sep;182:27–36. Available from: https://www.sciencedirect.com/science/article/pii/S0960076018300396
  24. Aboeldalyl S, James C, Seyam E, Ibrahim EM, Shawki HED, Amer S. The Role of Chronic Inflammation in Polycystic Ovarian Syndrome—A Systematic Review and Meta-Analysis. International Journal of Molecular Sciences. 2021 Mar 8;22(5). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7962967/
  25. Çıtar D., et al. The Effect on Inflammation of Adherence to the Mediterranean Diet in Polycystic Ovary Syndrome. Current Nutrition Reports, 2023;12(1):191–202. https://doi.org/10.1007/s13668-023-00451-6.
  26. Szczuko M, Kikut J, Szczuko U, Szydłowska I, Nawrocka-Rutkowska J, Ziętek M, et al. Nutrition Strategy and Life Style in Polycystic Ovary Syndrome—Narrative Review. Nutrients. 2021 Jul 18;13(7):2452. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308732/
  27. Mohan, A., et al. Vitamin D and polycystic ovary syndrome (PCOS): a review. Ann Med Surg (Lond). 2023;85(7):3506–3511. doi: 10.1097/MS9.0000000000000879.
  28. Wehr E, Pieber TR, Obermayer-Pietsch B. Effect of vitamin D3 treatment on glucose metabolism and menstrual frequency in polycystic ovary syndrome women: a pilot study. Journal of Endocrinological Investigation. 2011 Nov 1 [cited 2021 May 1];34(10):757–63. Available from: https://pubmed.ncbi.nlm.nih.gov/21613813/
  29. Chappell N, Schutt A. Hyperandrogenemia. Skinner MK, editor. ScienceDirect. Oxford: Academic Press; 2018. p. 70–6. Available from: https://www.sciencedirect.com/science/article/abs/pii/B978012801238364518X
  30. Nassar GN, Raudales F, Leslie SW. Physiology, Testosterone. PubMed. Treasure Island (FL): StatPearls Publishing; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK526128/
  31. Lehembre-Shiah, E., Gobioff, S., Yeshua, A., Peyser, A., & Maxwell, S. Prevalance Of Congenital Adrenal Hyperplasia (Cah) Carriers In Pcos Patients Seeking Fertility Treatment. Fertility and Sterility. 2023;120(1), e29. https://doi.org/10.1016/j.fertnstert.2023.05.058
  32. Yesiladali, M., et al. Differentiating Polycystic Ovary Syndrome from Adrenal Disorders. Diagnostics, 2022;12(9):2045. https://doi.org/10.3390/diagnostics12092045.
  33. Dokras, A., et al. Weight Loss and Lowering Androgens Predict Improvements in Health-Related Quality of Life in Women With PCOS. The Journal of Clinical Endocrinology and Metabolism, 2016;101(8):2966–74. https://doi.org/10.1210/jc.2016-1896.
  34. Sharma A, Welt CK. Practical Approach to Hyperandrogenism in Women. The Medical Clinics of North America. 2021 Nov 1;105(6):1099–116. Available from: https://pubmed.ncbi.nlm.nih.gov/34688417/
  35. NHS. Irregular Periods [Internet]. [cited 2024 Feb 21]. Available from: https://www.nhs.uk/conditions/irregular-periods/.
  36. NHS. When will my periods come back after I stop taking the pill? [Internet]. [cited 2024 Feb 21]. Available from: https://www.nhs.uk/conditions/contraception/when-periods-after-stopping-pill/.
  37. Singla, R., et al. Thyroid Disorders and Polycystic Ovary Syndrome: An Emerging Relationship. Indian Journal of Endocrinology and Metabolism, 2015;19(1):25–29. https://doi.org/10.4103/2230-8210.146860
  38. Legro RS, Arslanian SA, et al. Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology & Metabolism. 2013;98(12):4565–92. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399492/
  39. Kim, S., et al. What Is the Optimal Prolactin Cutoff for Predicting the Presence of a Pituitary Adenoma in Patients with Polycystic Ovary Syndrome? International Journal of Medical Sciences, 2023;20(4):463–67. https://doi.org/10.7150/ijms.80891
 

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