10% off €35 OR 15% off €45

Code:HOLLAND
 

10% off €35 OR 15% off €45

Code:HOLLAND

OffersBlack Friday DealsBuy One Get One 1/2 PriceBetter than 1/2 priceBuy 1 Get 1 Free Event25% off Online Only OfferOutlet2 for €23 Mix & MatchBuy 2 for €6 Mix & Match4 for €16 Mix & MatchVitamins & SupplementsVitamins & Supplements Shop AllCBDCollagen & SilicaHair, Skin & NailsShop all Hair, Skin & NailsHair GrowthFunctional MushroomsVitaminsShop all VitaminsMultivitaminsVitamin AVitamin BVitamin CVitamin DVitamin EVitamin KVitamin DrinksMineralsShop all MineralsMagnesiumIronZincCalciumSeleniumChromiumSupplementsShop all SupplementsFibre SupplementsAcidophilus & Friendly BacteriaPeppermint OilGrapeseed ExtractLecithinCollagen & SilicaOmega & Fish OilsPlant Sourced SupplementsSuperfood SupplementsArnicaApple CiderRaspberry KetonesAloe VeraChondroitin & MSMCo Enzyme Q10Evening Primrose OilGarlicGlucosamineGlucomannanSeaweed, Kelps and AquaceuticalsDigestive EnzymesSaw palmettoCharcoalWomen's HealthShop all Women's HealthMenopauseMenstrual SupportUrinary Tract HealthPregnancy & ConceptionMen's HealthShop all Men's HealthProstate HealthChildren's HealthConditionShop all ConditionCholesterolAllergy & Hay Fever CareAnxiety SupportBone & Muscle HealthMuscle Support & Joint PainBrain & Memory SupportWomen's HealthMen's HealthChildren's HealthCold & Immune SupportFatigueDigestive HealthHair, Skin & NailsHeart & CirculationLiver CareMood SupportSexual HealthSleep & RelaxationStress ReliefVisionHerbal & Licensed RemediesShop all Herbal & Licensed RemediesRescue RemedyAshwagandhaMilk ThistleGinseng & GuaranaHomeopathic & Flower RemediesShop all Homeopathic & Flower RemediesRescue RemedyFlower RemediesVegan Vitamins & SupplementsHolland & BarrettVitabioticsSolgarBetterYouNew NordicBioglanNatures AidDAMEDr OrganicGrass & Co.Black Friday DealsBuy One Get One 1/2 PriceBetter than 1/2 priceBuy 1 Get 1 Free Event25% off Online Only OfferOutlet3 for €18 Mix & MatchShort DatedDairy FreeGluten FreeSesame Seed FreeCelery FreeCereal FreeCrustaceans FreeEgg FreeFish FreeKiwi FreeLupin FreeNew inFood & DrinkChristmas Food & GiftsAdvent CalendarsFood & Drink Shop AllVegan FoodDried Fruit, Nuts & SeedsShop all Dried Fruit, Nuts & SeedsDried FruitNutsSeedsMixesChocolate CoatedTeas, Coffee & Hot BeveragesShop all Teas, Coffee & Hot BeveragesCoffee & Coffee SubstituteMushroom DrinksTeasMatcha & Green TeaSleep & Relaxation TeaSlimming TeaWomen's Health TeasHoney, Jams & SpreadsShop all Honey, Jams & SpreadsManuka HoneyHoneyNut ButtersJams & ChutneysSpreadsPateSuperfoodsShop all SuperfoodsSuperfood PowdersMoringa PowderSpirulinaGoji BerriesBaobabChia SeedsDrinks & JuicesShop all Drinks & JuicesMultipack DrinksProtein ShakesJuices & Health ShotsNatural Energy DrinksKombuchaSoft DrinksWaterAlcohol Free DrinksKefirSnacksShop all SnacksProtein BarsLow Calorie SnacksChocolate, Cakes & BiscuitsSavoury SnacksSweet SnacksSnack BarsCrisps & ChipsFlapjacksPopcornFood CupboardShop all Food CupboardCondiments & SaucesApple Cider VinegarSuperfoodsBreakfast CerealsHoney, Jams & SpreadsTinned FoodsRice, Pasta, Pulses & GrainsBreakfast CerealsShop all Breakfast CerealsCereals, Bran & FlakesGranolaMuesliOats & PorridgeBreakfast BarsCookingShop all CookingCooking IngredientsApple Cider VinegarCondiments & SaucesSoya & Meat AlternativeSoup & Ready MealsRice, Pasta, Pulses & GrainsHerbs, Spices & SeasoningGravy & StockHome BakingShop all Home BakingBaking MixesBreadFlourSweeteners & Sugar AlternativesEgg SubstitutesDairy AlternativesShop all Dairy AlternativesOat, Rice & Hemp DrinksSoya DrinksNut DrinksCoconut DrinksNutritionally Complete FoodHolland & BarrettGrenadeNaturyaPukkaHeath & HeatherNakdTwiningsMeridianPerfectTedOptimum NutritionBlack Friday DealsBuy One Get One 1/2 PriceBetter than 1/2 price25% off Online Only OfferBuy 1 Get 1 Free EventBuy 2 for €6 Mix & Match4 for €16 Mix & MatchOutletGluten FreeDairy FreeWheat FreeEgg FreeSugar FreeMilk FreeSoya FreeSesame Seed FreeCelery FreeFish FreeNew inSports NutritionSports Nutrition Shop AllProteinShop all ProteinClear ProteinProtein VeganMeal ReplacementsWhey ProteinMass GainersDiet ProteinCaseinSports SupplementsShop all Sports SupplementsSports CollagenBars, Drinks & SnacksShop all Bars, Drinks & SnacksEnergy BarsProtein BarsProtein ShakesProtein SnacksNutritionally Complete FoodMeal Replacement ShakesPre Workout & EnergyShop all Pre Workout & EnergyPre WorkoutAmino Energy DrinksAmino Energy PowdersIntra WorkoutKetoPost WorkoutAmino AcidsShop all Amino AcidsBCAAArginineCreatineShop all CreatineCreatine PowderRehydrationShop all RehydrationElectrolytesEnergy GelsVegan Sports NutritionShop all Vegan Sports NutritionVegan ProteinVegan Protein BarsVegan Pre Workout & EnergyVegan Amino AcidsVegan CreatineSports AccessoriesShop all Sports AccessoriesBottles & ShakersFitness GoalShop all Fitness GoalRecoveryMuscle & StrengthLean MuscleEnergy & EnduranceDiet & Weight LossKetoHolland & BarrettOptimum NutritionPrecision EngineeredGrenadeUSNApplied NutritionMyproteinPhDNakdSiSBlack Friday DealsBuy One Get One 1/2 PriceBetter than 1/2 price25% off Online Only Offer4 for €16 Mix & MatchBuy 1 Get 1 Free EventOutletGluten FreeDairy FreeSugar FreeWheat FreeEgg FreeMilk FreePalm Oil FreeSesame Seed FreeCelery FreeCrustaceans FreeNew inBeautyNatural Beauty Shop AllAromatherapy & HomeShop all Aromatherapy & HomePure Essential OilsBlended Essential OilsBase & Carrier OilsHolisticSkincareShop all SkincarePremium SkincareFace CareBody CareSun CareTanning & BronzingEye CareLip CareFoot CareHand & Nail CareCBD BeautyHair Skin & NailsShop all Hair Skin & NailsNail ConditionsSkin ConditionsCollagenWashing & BathingShop all Washing & BathingShampoo & ConditionerBathing AccessoriesShower Gel & Body WashDeodorantDentalHand WashSoapBath Soak & OilBody ScrubBath Bombs & SaltsFeminine CareIncontinence SupportHair CareShop all Hair CareShampoo & ConditionerHair ColouringHair MasksHair Oil & SerumHair Spray, Gel & MousseHair AccessoriesMother & BabyShop all Mother & BabyBaby Skincare & ToiletriesMakeupElectrical WellnessSexual WellnessDr OrganicFaith in NatureWeledaNaturtintHolland & BarrettTisserandMiaromaQ+ATrilogyEthiqueBlack Friday DealsBuy One Get One 1/2 PriceBuy 1 Get 1 Free EventBetter than 1/2 price2 for €23 Mix & MatchOutlet25% off Online Only OfferAlcohol FreeDairy FreeGluten FreeParfum FreePalm Oil FreeMicroplastics FreeSesame Seed FreeSoya FreeCelery FreeCereal FreeNew inWeight ManagementWeight Management Shop AllSlimming TabletsFat Burners, Binders & Appetite SuppressantsShop all Fat Burners, Binders & Appetite SuppressantsFat BurnersFat BindersAppetite SuppressantsShakes & Weight Management ShotsShop all Shakes & Weight Management ShotsMeal Replacement ShakesWeight Management ShotsDiet Food & DrinkShop all Diet Food & DrinkDiet FoodLow Calorie SnacksSlimming TeaExercise SupportHolland & BarrettGrenadeOptimum NutritionHeath & HeatherPulsinUSNDiabloEat WaterGreenPeppersmithBlack Friday DealsBuy One Get One 1/2 Price25% off Online Only OfferBetter than 1/2 priceBuy 1 Get 1 Free EventGluten FreeSugar FreeDairy FreeWheat FreeMilk FreeCelery FreeCereal FreeCrustaceans FreeEgg FreeFish FreeNew inChristmasHealth & WellnessShop all Health & WellnessJoints Bones & MusclesEnergyGut HealthShop all Gut HealthGut Health FoodHair Skin & NailsShop all Hair Skin & NailsNail ConditionsSkin ConditionsCollagenStress AnxietyShop all Stress AnxietyEnergy SupportSleep & RelaxationShop all Sleep & RelaxationRelaxationFood & DietShop all Food & DietKeto FoodMenopauseHolland & BarrettNaturtintDr OrganicVitabioticsApplied NutritionOptimum NutritionWildWeledaSolgarNew NordicBlack Friday DealsBuy One Get One 1/2 PriceBetter than 1/2 priceBuy 1 Get 1 Free Event25% off Online Only Offer2 for €23 Mix & MatchOutlet3 for €18 Mix & MatchDairy FreeGluten FreeSugar FreeAlcohol FreeWheat FreeEgg FreeSesame Seed FreeCelery FreeCrustaceans FreeFish FreeNew inShop for your WellnessGut HealthImmunityEnergyWomen's HealthMenopauseSkincareJoints, Bones & MusclesHair, Skin & NailsSleep & RelaxationFood & DietChildren's HealthStress ReliefHealthy HeartLow Mood & DepressionEye HealthSexual HealthLearn about WellnessJoints, Bones & MusclesWomen's HealthPeriod & Cycle HealthMenopauseImmunityGut HealthFood & DietSports & FitnessSleep & RelaxationHair Skin & NailsArticlesAll articlesHealthFood & nutritionGut healthImmunityJoints, bones & musclesWomen's healthWellnessHair & skinMental wellbeingSeasonalSleep & relaxationSports nutritionRecipesAll recipesGluten freeLow sugarVeganDairy freePodcast

How healthy is sunflower oil?

sunflower oil bottle with seeds and fresh flower
In the age of gourmet oils, sunflower oil doesn’t stand out. But is it really so bad for you? It actually holds some impressive health benefits, as long as you know which type to choose.

These days, there are so many oils to choose from. Whether you’re looking for an oil to use in your cooking, skin or haircare routine, or for your family’s general use, there’s never been more options.

But is sunflower oil healthy?

Is sunflower oil better than olive oil?

Depending on who you ask, sunflower seed oil is either a versatile, healthy oil – or to be avoided at all costs.

The reality is a little more complicated. Sunflower oil can be a healthy choice – but there are a few things to bear in mind.

What is sunflower oil? 

Sunflower oil is made from pressing sunflower seeds – harvested from the sunflower plant helianthus annuus – to extract their oil.1

Sunflower oil has increased in prevalence over the past century, primarily due to a changing diet across the Western world.

It’s used as a frying oil, in the manufacture of mayonnaise and oil‐based dressings as well as to make shortenings and margarines. Industrial uses include the manufacture of biodiesel, industrial lubricants, ink and cosmetics.2

Is sunflower oil good for health?

Is sunflower oil good for you? Nutrients in sunflower oil include a high level of vitamin E, which is an antioxidant that can help protect cells from oxidative damage. Oxidative damage can lead to various diseases, as well as premature ageing.3

Sunflower oil is also low in saturated fat and contains both monounsaturated and polyunsaturated fats in the form of omega 3 and omega 6 essential fatty acids – both required for a healthy diet.4

Impressively, the unsaturated fats in sunflower oil have shown to reduce levels of LDL (bad) cholesterol and raise the levels of HDL (good) cholesterol after being included in the diet for six months.5 This could be beneficial in helping to protect you from cardiovascular disease.

It’s worth bearing in mind that sunflower oil usually does contain some saturated fat, in the form of stearic acid. However, stearic acid is the only saturated fat which doesn’t raise LDL cholesterol.6

Sunflower oil calories are high as is typical of any oil – at 124kcal per tablespoon, so you shouldn’t have too much, or it can cause weight gain.7

The key to whether sunflower oil is a healthy choice lies in the composition of fats it contains.

The fat composition of sunflower oil 

Sunflower oil contains both types of unsaturated fat – monounsaturated fat and polyunsaturated fat.8

  • Monounsaturated fat – in the form of the omega 3 fatty acid oleic acid
  • Polyunsaturated fat – in the form of the omega 6 fatty acid linoleic acid

Polyunsaturated and monounsaturated fats can be good choices to help you cut down on saturated fats in your diet. Remember, too much saturated fat can elevate your levels of LDL (or ‘bad’) cholesterol.9

Omega 3 fatty acids are known to have anti-inflammatory properties, whereas omega 6 fatty acids can actually cause inflammation in the body when we get too many of them. Inflammation is a key factor in the development of many diseases, including heart disease and cancer.10

However, we need both omega 3 and omega 6 fatty acids – in different amounts – to stay healthy.

Some scientists believe that the ideal ratio of omega 6 to omega 3 fatty acids is 1:1, although the modern Western diet is closer to 17:1 omega 6 to omega 3.11

Different sunflower oils contain different ratios of omega 3 and omega 6. It’s the sunflower oils which are higher in omega 3 (oleic acid) than omega 6 (linoleic acid) which are considered healthiest.

There are four main types of sunflower oil composition12:

  • High-oleic sunflower oil is 75–91% oleic acid. It’s also highest in omega 3, with a smaller amount of omega 6. This is the healthiest choice. Oleic acid has been shown to help lower LDL (or ‘bad’) cholesterol and raise the HDL (or ‘good’) cholesterol.13
  • Mid-oleic (about 43–72% oleic acid) has higher omega 3 than omega 6 but doesn’t contain as much omega 3 as the high-oleic variety.
  • High-oleic with stearic acid – high in omega 3 and lower in omega 6, this is also considered healthy.
  • High-linoleic is highest in omega 6, with a smaller amount of omega 3 (about 14–39% oleic acid). High-linoleic sunflower oil is the type associated with inflammation.

Today, thanks to plant breeding, there are plenty of varieties of sunflower oil with a high composition of oleic acid, so it should be relatively easy to find in shops.14

Summary 

  • Made from pressing sunflower seeds, sunflower oil is one of the world’s most prevalent oils 
  • Sunflower oil contains the antioxidant vitamin E, as well as healthy unsaturated fats 
  • High-oleic sunflower oils are rich in omega 3 fat and can help reduce inflammation 
  • High-linoleic sunflower oils have higher levels of omega 6 fat and can cause inflammation 

Which is the best sunflower oil for cooking? 

You might have heard about using sunflower oil for frying, as it has a high smoke point. This means it can be heated to a high temperature (around 230C) before it starts to smoke.

However, polyunsaturated fats (such as those found in sunflower oil) become oxidised when heated, giving off free radicals which are harmful to health.14

So – how can sunflower be a good oil to cook with if it becomes toxic when heated?

Again, it’s about the type of sunflower oil you choose.

The high-linoleic type of sunflower oil is the type which is considered ‘volatile’, ‘unstable’ and unsuitable for cooking. If you want to use sunflower oil for deep frying, be aware that it’s only high-oleic sunflower oil that is suitable for high heat cooking.16

To further ensure the sunflower oil you’re choosing offers the health benefits you’re after, ensure that it’s cold pressed sunflower oil. If an oil isn’t labelled ‘cold-pressed’, the oil has likely been extracted from the seed using high heat.

Remember, high heat degrades sunflower oil and can cause oxidation and the release of free radicals.

It’s also a good idea to choose organic sunflower oil, which will have been grown without any pesticides and GMOs, so you can be sure the oil is free from adulterations.

What is the healthiest oil to cook with? 

So, how does sunflower oil stack up in comparison to other popular cooking oils? We take a look at some pros and cons to find out.

  • Sunflower oil 

Pros: With 41g of vitamin E per 100g, sunflower oil has twice as much of this antioxidant as olive oil.

Sunflower oil is rich in polyunsaturated and monounsaturated fatty acids, comprising the omega 3 oleic acid and omega 6 linoleic acid which is anti-inflammatory and can help lower LDL (bad) cholesterol.17

Sunflower oil is low in saturated fat with 10.3g saturated fat per 100g.

Cons: High-linoleic sunflower oil contains a relatively high level of pro-inflammatory omega 6 fats.18

Sunflower oil only contains 5.4mcg of vitamin K per 100g, less than some other oils.

  • Olive oil 

Pros: With 14g vitamin E per 100g, olive oil is a good source of this antioxidant. Olive oil also lots of vitamin K with 60mcg vitamin K per 100g.19

Olive oil is rich in monounsaturated fatty acids, including a high content of oleic acid as well as potent anti-inflammatory compounds such as oleocanthal.20

Olive oil is low in saturated fat, with 13.8g saturated fat per 100g.

Cons: Olive oil is considered by many to be the king of oils, due to its health benefits and versatility. It’s not great for deep-frying, however, as it’s not stable after about 160C.21

  • Coconut oil 

Pros: Coconut oil contains traces of iron, calcium and vitamin E.22 The fats in coconut oil can raise the levels of HDL (good) cholesterol in the body.23

Cons: Coconut oil is 82% saturated fat which might be bad news for anyone watching their weight or at risk of high cholesterol.

  • Soybean oil 

Pros: Soybean oil contains a little vitamin E, with 8g per 100g. It’s very high in vitamin K, with 183mcg per 100g.24

It’s low in saturated fat at around 15%, and high in polyunsaturated fats which could have protective effects on cardiovascular health.25

With a high smoke point of around 230C, it’s good for deep frying.26

Cons: With a high ratio of omega 6 to omega 3 fats, soybean oil should be used sparingly in favour of higher omega 3 oils like olive and high-oleic sunflower oils.

  • Canola oil 

Pros: Canola oil contains 17g of vitamin E per 100g and is high in vitamin K with 71mcg per 100g.27

It’s very low in saturated fat at only around 7%, and with a smoke point over 200C, it’s a decent choice for frying.28

Canola oil contains healthy polyunsaturated omega 3 fats.

Cons: Canola oil can contain up to 4.2% trans fats, which are harmful to health, so always check the label.29

  • Sesame oil 

Pros: Sesame oil contains 13.6g vitamin K per 100g and is low in saturated fat at around 14%.30 It’s shown in study to be useful in helping to lower LDL (bad) cholesterol and inflammation thanks to its polyunsaturated fat content.31

With a smoke point around 210C, you can deep fry with light sesame oil.32

Cons: With only 1.5mcg of vitamin E per 100g, that’s lower than most oils.

  • Peanut oil 

Pros: Peanut oil contains around 15.6g of vitamin E per 100g.33 It’s low to medium in saturated fat with around 17g per 100g, as well as containing LDL (bad) cholesterol-reducing monounsaturated and polyunsaturated fats.34

It’s got a high smoke point at 232C, so it’s fine to fry with.35

Cons: It only contains traces of vitamin K with 0.7mcg per 100g. Peanut oil is also a little high in pro-inflammatory omega 6 fats to be considered a perfect choice.

Can you use sunflower oil for skin?

Putting the same stuff they use to fry chips onto your face might not seem like a beauty secret you’d want to copy, but hear us out.

Sunflower oil’s outstanding vitamin E content (more than any other oil!) means that it’s perfect for applying topically to your skin.

Vitamin E has emollient properties, meaning it helps keep moisture inside the skin, helping it look plump and hydrated. Vitamin E is also an antioxidant which can help prevent oxidative damage to cells which cause visible ageing of the skin.36

You can use sunflower oil as a moisturising treatment on both the face and body. Apply after bathing or showering for best results.

Can you use sunflower oil for hair? 

As with skin, sunflower oil is nourishing and hydrating for both hair and scalp.

You could use a drop as a serum for dry, damaged ends. It’s very rich, so a little goes a long way.

For an all-over nourishing hair mask which will impart shine and treat a dry scalp, use gently warmed sunflower oil (a few seconds in the microwave is all it takes) and massage from roots to ends. Cover with a shower cap and leave for 30 minutes before shampooing out.

Summary 

  • Sunflower oil benefits can include lowered cholesterol and reduced inflammation
  • We need more omega 3 fats than omega 6 fats for optimal health
  • The high-oleic variety of sunflower oil contains more omega 3 fats than 6, and is considered beneficial for health
  • High-oleic sunflower oil is recommended for cooking
  • Sunflower oil is great for skin and hair
The advice in this article is for information only and should not replace medical care. Please check with your GP or healthcare professional before trying any supplements, treatments or remedies. Food supplements must not be used as a substitute for a varied and balanced diet and a healthy lifestyle.

Last updated: 23 April 2021

Sources

  1. https://www.alimentarium.org/en/knowledge/sunflower-oil
  2. https://onlinelibrary.wiley.com/doi/10.1002/047167849X.bio017.pub2
  3. https://pubmed.ncbi.nlm.nih.gov/16011463/
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269634/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473013/
  6. https://link.springer.com/article/10.1007/s13593-017-0426-x/
  7. https://fdc.nal.usda.gov/fdc-app.html#/food-details/1103867/nutrients
  8. https://www.degruyter.com/document/doi/10.1515/helia-2014-0010/html
  9. https://openheart.bmj.com/content/5/2/e000871
  10. https://pubmed.ncbi.nlm.nih.gov/12442909/
  11. https://www.sciencedirect.com/science/article/abs/pii/S0753332206002435
  12. https://onlinelibrary.wiley.com/doi/10.1002/047167849X.bio017.pub2
  13. https://pubmed.ncbi.nlm.nih.gov/15983523/
  14. https://www.downtoearth.org.in/news/climate-change/making-sunlight-liquid-a-brief-history-of-sunflowers-61431
  15. https://pubmed.ncbi.nlm.nih.gov/18967717/
  16. https://pubmed.ncbi.nlm.nih.gov/23870970/
  17. https://fdc.nal.usda.gov/fdc-app.html#/?query=%20oil
  18. https://www.sciencedirect.com/topics/medicine-and-dentistry/omega-6-fatty-acid
  19. https://fdc.nal.usda.gov/fdc-app.html#/?query=%20oil
  20. https://pubmed.ncbi.nlm.nih.gov/16136122/ 
  21. https://www.masterclass.com/articles/cooking-oils-and-smoke-points-what-to-know-and-how-to-choose#chart-of-oil-smoke-points
  22. https://fdc.nal.usda.gov/fdc-app.html#/?query=%20oil
  23. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855206/
  24. https://fdc.nal.usda.gov/fdc-app.html#/?query=%20oil
  25. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719153/
  26. https://www.masterclass.com/articles/cooking-oils-and-smoke-points-what-to-know-and-how-to-choose#chart-of-oil-smoke-points
  27. https://fdc.nal.usda.gov/fdc-app.html#/?query=%20oil
  28. https://www.masterclass.com/articles/cooking-oils-and-smoke-points-what-to-know-and-how-to-choose#chart-of-oil-smoke-points
  29. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1745-4522.1994.tb00244.x  
  30. https://fdc.nal.usda.gov/fdc-app.html#/?query=%20oil
  31. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587404/
  32. https://www.masterclass.com/articles/cooking-oils-and-smoke-points-what-to-know-and-how-to-choose#chart-of-oil-smoke-points
  33. https://fdc.nal.usda.gov/fdc-app.html#/?query=%20oil
  34. https://www.jrnlappliedresearch.com/articles/Vol8Iss3/216-225_SalesVol8No3.pdf
  35. https://www.masterclass.com/articles/cooking-oils-and-smoke-points-what-to-know-and-how-to-choose#chart-of-oil-smoke-points
  36. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976416/
 

Related Articles